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A: They are prescribed to manage type 2 diabetes and obesity by improving blood sugar control and promoting weight loss
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Additional safety considerations include tirzepatide's boxed warning for thyroid C-cell tumors, risk of pancreatitis (symptoms include severe persistent abdominal pain, sometimes radiating to the back), gallbladder disease, and potential complications in patients with diabetic retinopathy
The potential molecular mechanisms underlying these effects included disturbances in redox homeostasis (as evidence by the enhanced production of ROS and reactive nitrogen species), failure of enzymatic and nonenzymatic cytoprotective mechanisms involving the glutathione system as well as nuclear factor kappa B (NF-B) and fibroblast growth factor 2-mediated pathways, and impaired mitochondrial function
Acne There is some concern that it may contribute to acne breakouts
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