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Glutathione is one of the most potent endogenous antioxidants, playing a central role in neutralizing reactive oxygen species (ROS) and protecting cells from oxidative damage - a key factor in aging and metabolic stress
Threlfell, Sarah, et al
Thus, the half-life of superoxide, although very short at high concentrations (e.g., 0.05 seconds at 0.1mM) is actually quite long at low concentrations (e.g., 14 hours at 0.1 nM)
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Chronic niacin deficiency leads to pellagra, a condition now rare in developed countries due to its association with poor nutrition, resulting from low intake of niacin or tryptophan (5, 11, 12)
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