how much can i lose on tirzepatide Long Does It Take to 50 Pounds (Zepbound or Mounjaro)? Weight Loss That Actually Works:

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This medication works by mimicking a hormone called GLP-1 (glucagon-like peptide-1), which regulates appetite and food intake

Todays approval is another demonstration of what the FDA can accomplish when we try bold new things. The higher-dose GLP-1 is indicated to reduce excess body weight and maintain weight reduction long-term in adults with obesity, or overweight with at least one weight-related condition, per the FDAs statement

doi:10.1038/s41591-024-02970-5 PubMed: This substudy demonstrated that retatrutide reduced liver fat by 81-82% at the 8mg and 12mg doses over 24 weeks, providing evidence of retatrutides multi-system metabolic benefits beyond weight loss

This finding led to semaglutide being approved as a weight loss treatment under certain conditions