SGLT2 inhibitor effects have been established on cardiomyocytes, endothelial cells, fibroblasts, and smooth muscle cells (Uthman et al., 2018a
Providers should counsel against expecting sustained 2+ lbs/week loss indefinitely
This transition is essential to keep in mind when planning trials that concentrate on geroscience, as it will ultimately impact the selection of biomarkers for monitoring and enhance existing therapeutic strategies, specifically addressing the biological processes of aging at the physiological systems level
Most GLP-1 medications do not significantly affect the blood levels of standard oral contraceptive pills
The drug companies believe that hitting more receptors induces better weight-loss effects, which does appear to be true, but when it comes to what this is doing across different immune populations, downstream signaling can be completely changed by adding on these extra agonists, she says