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A reduction in the cost would shift the balance of this cost effectiveness, potentially paving the way for their longer-term use especially when coupled with research showing the reversal of weight loss after patient stop taking them, and the continued benefit in cardiovascular risk associated with longer term use. Dr Ivan Koychev of the University of Oxford, who is researching the application of GLP-1 analogues in dementia patients, said demand for such drugs was currently outstripping supply as a result of the high prevalence of obesity and type 2 diabetes

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Lipid oxidation, in Food and biological systems: a physical Chemistry Perspective (Cham: Springer International Publishing), 341359

The consistent increase under professional supervision helps patients build tolerance while carefully monitoring progress, making adjustments as needed based on individual reactions