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Description

Within its N-terminal domain, GLP-1R contains six conserved cysteine residues that form specific disulfide bonds between Cys46-Cys71, Cys62-Cys104, and Cys85-Cys126 [30]

It is studied as a dual GIP and GLP-1 receptor agonist in metabolic research models

CTA assay A week before the study start (day 7), rats were single-housed with ad libitum access to chow diet and one bottle of water (food and water were placed in the cage lid so that there was room for two water bottles)