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[31] The products are usually extracted and purified by phenol-methylene chloride extraction or by column chromatography
NICE-recommended, MHRA-licensed alternatives in the UK include orlistat (Xenical/Alli), semaglutide 2.4 mg (Wegovy), liraglutide 3.0 mg (Saxenda), and tirzepatide, all prescribed within structured clinical programmes based on BMI and comorbidity eligibility criteria
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However, some individuals may struggle to maintain adequate vitamin B12 through their diet alone
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