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Since previous studies have linked the activation of NRF2 with the repression of lipogenic gene expression 64 , we reasoned that GSH depletion causes oxidation and consequent inactivation of KEAP1 (a repressor of NRF2), thus leading to increased antioxidant and decreased lipogenic gene expression
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Jha U, Asad M, Asdaq SMB, Das AK, Prasad VS
Another population-based study in South Korea comparing the use of DPP4-inhibitors with other oral glucose lowering agents ( sulfonylurea, thiazolidinedione , and metformin ) showed that the overall risk of diabetic retinopathy events was not increased (Kim et al., 2018)
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