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In the REWIND study, DR was defined as photocoagulation, anti-vascular endothelial growth factor therapy, or vitrectomy [8], whereas DR was determined when patients had vitreous hemorrhage, the onset of diabetes-related blindness, and the need for treatment with an intravitreal agent or retinal photocoagulation in the SUSTAIN-6 [9] and LEADER trials [10]
Taste changes may relate to delayed gastric emptying, GLP-1 receptor activity in taste buds and brain reward centres, or accompanying gastrointestinal symptoms like nausea
These capsules are used in the treatment of a wide range of conditions
There are also three peptide YY (PYY) agonists and two GLP-1/PYY dual agonists currently in phase 1 or phase 2 studies
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