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otology 15 (2), 229236
View image online ( Glucagon-like peptide-1 (GLP-1) receptor agonists and GLP-1 receptor/glucose-dependent insulinotropic polypeptide (GIP) receptor dual agonists bind to their respective receptors on pancreatic beta cells to stimulate glucose-induced insulin secretion
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This dual mechanism is what separates tirzepatide from older GLP-1 medications like semaglutide , which only activate the GLP-1 receptor
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