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10 Conclusion and perspectives DKD, a serious DM-related microvascular disorder, is pathologically defined by persistent hyperglycemia-triggered complex metabolic abnormalities, ultimately leading to glomerular filtration barrier destruction and tubulointerstitial injury (8, 10)
doi: 10.1038/nm.4345 136 WulffelM
ECG assessments are performed at randomization, and weeks 52, 104, and 156
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