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Brain reward circuitry beyond the mesolimbic dopamine system: a neurobiological theory
Its symptoms (agitation, high fever, rapid heartbeat, sweating, confusion, muscle rigidity, seizures) require immediate medical attention and supportive care
In terms of the anorectic pathways in the brain, the anorectic effects of MC4R agonism are mediated by downstream responses of POMC/CART neurons [26, 27]
Doing so could increase the risk of severe side effects or complications
[2] A broader review of 24 RCTs found spironolactone 100 mg/day reduced FG score more than finasteride or cyproterone acetate in idiopathic hirsutism
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