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Injections can cause minor effects such as irritation or itching at the injection site, and the consumer fact sheet is a good plain-language reference on what B12 does and does not do

12 Case reports in the medical literature describe U.S

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- Use a dedicated container or small box to prevent the vial from being knocked over

Higher concentrations (0.1% or above) risk copper overload on compromised skin, which can trigger the copper uglies: persistent redness, breakouts, and worsening sensitivity