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Compounded medications like MIC+B12 are prescribed individually and not mass-produced, so they are not reviewed by the FDA
For most people, SQ shots are much less painful than IM shots because muscle tissue has a significantly higher density of nerve endings
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According to StatPearls (NCBI Bookshelf), the most common adverse effect of intramuscular vitamin B12 injections is significant pain at the injection site, which is particularly noted in thinner individuals
At the starting dose of 2.5mg per week, a 10mg vial lasts four weeks
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