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Therefore it is timely to review the evidence that supports its use at both molecular and clinical levels

Third-party COA: Look for HPLC purity testing per batch from an independent ISO/IEC 17025-accredited lab

doi: 10.1038/s41581-022-00601-z 70 SpinelliRBabootaRGoggSBeguinotFBlherMNerstedtAet al

e,h , Observed adducts and fragments in negative ( e ) and positive ( h ) ion ESI-MS, their calculated monoisotopic masses, as well as the expected and observed number of 18 O incorporations