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synthesized nanoclusters possessing multiple high Z elements, such as Fe 3+ and W 6+ , to give them the ability of remarkable GSH exhaustion and amplified ROS generation upon radiation, both of which have been prevalently exploited as promising anticancer methods (Zhou et al., 2019)

Competing interests All authors declare that they have no commercial or other associations that may pose a conflict of interest

Mechanisms of tumor resistance to immune checkpoint blockade and combination strategies to overcome resistance

Furthermore, GHK-Cu prevents collagen-degrading enzymes such matrix metalloproteinases, protecting the structural integrity of the skin

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