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GLP-1 receptor agonists are meant to be taken long-term, but that will look different for each individual

"My patients had been complaining about this

Because retatrutide has not yet received regulatory approval in the UK, there is currently no defined patient population for whom it is formally indicated

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Worryingly however, 26.8% of patients had to discontinue the trial due to the severity of side-effects, although it must be noted that this was in part due to the lack of a run-in (A time frame where drug dosage is started from a low dosage and then escalated over time until the highest tolerable dose for the patient is reached) [40]