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Tryptophan is an amino acid that the body produces naturally, and this is vital for helping the body to feel drowsy and fall asleep at night

DSM-5 defines ASD as a persistent condition affecting two core areas: social communication and restricted or repetitive behaviors

Activation of nuclear factor-B (NF-B) induces transcription of target genes that primarily encode survival proteins (e.g., cellular FLICE-like inhibitory protein and inhibitor of apoptosis proteins) via formation of the complex I signalosome after binding to TNF receptor-1

Differences between samples were assessed using independent two-tailed t-tests or analysis of variance (ANOVA)

doi: 10.1016/j.ctcp.2016.11.008 149 ChenJGuoQY-HPRenQ-LChiLHuR-Ket al