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Back Rehfeld, JF (2018) 'The origin and understanding of the incretin concept', Frontiers in Endocrinology' , 9, 387

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The honest cautions: much of the mechanistic depth still comes from animal models, we need longer and larger human trials, and allulose can cause bloating or loose stools at higher doses, as most poorly absorbed sugars can

First, they act on the appetite centers in your brain to reduce hunger and food cravings

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