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The maximal emission was reached 36 h after injection of the nanoparticles (animal imaging: Fig
, Indeed, related to b0,+ amino acid transporter expression was detected exclusively in the proximal tubules, indicating active cystine reabsorption under physiologic conditions (Figure 1I)
The primary structural difference is that Melanotan 1 is a linear peptide that mimics the full length of natural -MSH
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