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While the list of pathophysiologic defects continues to grow, the ominous octet provides a representation of 8 key defects found in T2DM ( Figure 1 )
PEIA opted to pause the program in 2024 citing a $1.3 million per month price tag, inclusive of rebates
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Eli Lilly and Novo Nordisk have each worked to reduce the price for cash-paying patients (both have cash programs for their weight loss products for around $500 per month) but have not come close to the pricing accessibility that compounders and vendors of compounded products have been offering
We identified patents and their patent family members that could either be used to deter other branded competitors from upstream research and development of competing similar products (e.g., me-too versions), or which could be used downstream to block/delay generic entrants
