A Cleveland Clinic review notes that one case report described symptoms only after a cumulative 15,000 mcg (15 mg) of injected B12 over several weeks
3) Injected Joint: Occasionally pain(mostly temporary pain after injection), sweling, rarely dropsy, rebefaction, hot flush, pressure on joint and ecchymosis can appear
See tips for reducing these side effects in our Fish Oil Supplements Review, which includes our Top Picks among fish, krill, and algal oil supplements
Food and Drug Administration Updated 503A bulk drug substances list (Category 2 revision, effective April 22, 2026)
NAD+ and NADH in cellular functions and cell death [PMID: 16720381] Laboratory literature summary: NAD+ and NADH in cellular functions and cell death