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delbrueckii was shown to produce high volumes of diacylglycerola precursor lipid that the host organism converts into the native endocannabinoid 2-arachidonoylglycerol (2-AG)
In professional body cosmetics, it is integrated as support in protocols aimed at improving the appearance of localised fat deposits
It is particularly important for neurological and cognitive health
17 This involves a combination of in vitro (within a test tube or glass) and in vivo (within a living organism) studies that must establish six essential components 18 : Creation of drug substance/active pharmaceutical ingredient Dosage design (formulation) Analytical and bioanalytical method development and validation Metabolism and pharmacokinetics (PK) Toxicology and pharmacologic safety Current Good Manufacturing Practice (cGMP) and documentation of the drug candidate for use in clinical trials At this point, a drug developer can submit an Investigational New Drug (IND) application to the FDA, which includes data from preclinical animal tests and the plan for human trials
