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Functionally, Melanotan II binds and activates the human melanocortin receptors MC1R, MC3R, MC4R, and MC5R with affinity comparable to (and in some assays exceeding) native -MSH

PMC Xie X, et al

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GPx7 likes to interact with the domain of PDI, and intramolecular cooperation between the two redox-active sites of PDI increases the activity of the Ero1/GPx7/PDI triplet, thereby promoting protein folding mechanisms (Wang et al., 2014) (Figure 6)

We also hand-searched reference lists of relevant articles and searched for relevant studies from the abstract of conferences