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In fact, for every 500 g of oral B12 supplement ingested, only about 10 g is absorbed
Choice of formulation is therefore guided mostly by clinical goals, availability and cost
Some phenotypes plausibly need a slower-than-label climb: lighter bodies (higher exposure per milligram), a history of severe GLP-1 gut intolerance, a high baseline heart rate, or a lean, low-reserve build
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