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Results were analysed using Magellan 6.0 software (Tecan, Germany)

Liver and pancreatic effects Transient increases in liver enzymes (ALT) exceeding three times the upper normal limit occurred in roughly 1% of participants receiving retatrutide

Raster Image Correlation Spectroscopy (RICS) image capture and analysis INS-1 832/3 SNAP/FLAG-hGLP-1R WT or V229A cells were seeded onto glass bottom MatTek dishes and labelled with SNAP-Surface 647 (S9136S, New England Biolabs) for 15 minutes at 37C in full media, washed and imaged in RMPI-1640 media without phenol red using a 100X oil objective on a Leica Stellaris 8 STED FALCON microscope from the FILM Facility at Imperial College London using confocal settings as previously described (81)

Chemical and in vitro toxicological comparison of emissions from a heated tobacco product and the 1R6F reference cigarette

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