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The IGF-1 signaling axis is widely studied for its involvement in cellular proliferation, metabolic regulation, tissue growth, and intracellular signaling mechanisms in preclinical research models
CROI: Effects of Semaglutide on Muscle Structure and Function in the SLIM Liver Study - (03/12/24) Semaglutide at CROI 2024 the use of semagltude is found to cause muscle loss in PWH in these studies, as well as worsening already existing or causing facial & limb fat loss/lipoatrphy, this this becomes a concern for WPWH aging were muscle & fat changes or loss can be impactful
2 The study has important limitations, as outlined below, but its the first to examine GLP-1 medications specifically in fibromyalgia
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