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Importantly, the loss of Bdnf gene expression in the dentate gyrus eliminated the antidepressant-like behavioral effects of leptin, suggesting that upregulation of BDNF underlies leptins action on mood-related behavior

De S Coutinho D, Pacheco MT, Frozza RL, Bernardi A

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The brand is open to the fact that this product might be a bit sticky, and your might smell it a little bit, but it goes away