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Both of them are great for weight loss, but bariatric surgery has the longest track record of sustained weight loss. Jafri added that although GLP-1s are now considered an effective and convenient way to lose weight, the weight loss typically requires long-term therapy with possible increasing cost to the patients

In studies for weight loss, semaglutide has helped people lose 10-15% of their body mass

The guidelines state, GLP-1 RAs may be considered for weight-loss in patients who have completed cancer therapy and may be considered with caution for patients on stable endocrine-based cancer therapies based on limited observational safety data. They also say, GLP-1 RAs cannot be recommended currently for patients receiving or initiating chemotherapies and/or immunotherapies due to lack of safety and outcomes data. Iyengar is director of Survivorship Services at Winship Cancer Institute of Emory University, a clinical member of Winships Glenn Family Breast Center, an associate professor and co-director of the Breast Medical Oncology Program in the Department of Hematology and Medical Oncology at Emory University School of Medicine, and co-editor-in-chief of the journal ONCOLOGY

Its because they are encapsulated in lipids, improving their efficacy and absorption when compared to the normal forms

We would welcome further research which investigates this observation and the underlying mechanisms