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That is the entire structural difference

Gut Microbes 13(1):1927633 Ruart M, Chavarria L, Camprecis G, Surez-Herrera N, Montironi C, Guix-Muntet S, Hernndez-Gea V (2019) Impaired endothelial autophagy promotes liver fibrosis by aggravating the oxidative stress response during acute liver injury

The amino acid sequence and domain structure of schistosome TGR has similarities to mammalian forms of TrxR and GR, with an additional amino-terminal extension of a glutaredoxin (Grx) domain of ~110 amino acids with a typical CPYC active site [11]

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