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This simultaneous tri-receptor engagement represents a mechanistic departure from earlier compounds in the incretin class, which targeted one or two of these receptors
10.1210/jcem.81.1.8550773 11
This means we're desensitized to it, which can lead to type 2 diabetes, cardiovascular disease, metabolic syndrome and more
Wegovy (injectable semaglutide), Saxenda (liraglutide), and Zepbound (tirzepatide) are some of the popular ones
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