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CONTRAINDICATIONS According to the package insert, Mounjaro and Zepbound is contraindicated in patients with the following: personal or family history of Medullary Thyroid Carcinoma patients with Multiple Endocrine Neoplasm type 2 patients with a prior serious hypersensitivity reaction to tirzepatide or to any of the excipients in Mounjaroand Zepbound
The SURMOUNT-4 trial demonstrated that participants who discontinued tirzepatide after initial weight loss regained significant weight (approximately 14% regain over 52 weeks following randomized withdrawal), while those continuing treatment maintained their weight loss, confirming ongoing medication efficacy
Avoid overly rich, creamy, fried and high-fat foods to minimise potential digestive issues
Many people who think they need a higher dose actually need better absorption from the dose they are already taking
A few years later, Baxter enlisted Flier with a new task: to start a new company focused on diabetes and obesity
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