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Laboratory studies in animals indicate that GLP-1 RAs target hallmarks of brain aging and may activate neuroprotective pathways that promote cellular waste removal, reduce neuroinflammation, promote mitochondrial health and regeneration which may alleviate symptoms of cognitive decline in models of Parkinsons and Alzheimers diseases

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Similar results were described by Delforge regarding OS with adequate ICT and no adequate ICT (p = 0.001) but not between weak ICT and no ICT (148)

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Compounded Tirzepatide is dispensed through licensed 503A compounding pharmacies under individual patient prescriptions the compounding pathway is regulated by state pharmacy boards and the FDA but does not require pre-market approval as a branded product

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