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Does NAD cause weight gain
Fernndez-de-Las-Peas C, Palacios-Cea D, Gmez-Mayordomo V, Cuadrado ML, Florencio LL
LiNLiXDingYLiuXDiggleKKisselevaTet al
This extraordinary potency arises from the combination of the D-phenylalanine substitution at position 7, which confers enzymatic resistance and enhanced receptor binding geometry, the Nle substitution at position 4 that prevents methionine oxidation, and the cyclic lactam constraint that pre-organizes the pharmacophore into the bioactive conformation
Ludwig, A
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