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Organisms have developed a highly conservative and complex molecular clock system, which creates an internal circadian rhythm during light/dark input ( SCN may act on somatostatinergic neurons and GH-releasing hormones (GHRH) to synchronize the GH rhythm with the light-dark cycle (Willoughby and Martin, 1978
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The two pathways converge to produce GH release with characteristics neither agent produces alone
A healthcare professional should administer the injection
