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Some practitioners theorize that local abdominal injection may enhance regional fat mobilization, though this has not been conclusively proven in research

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Ma J, Yang L, Ren J, Yang J

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Indeed, in the cardiovascular outcome trial (CVOT) for semaglutide, SUSTAIN 6 a relatively short (two-year) and small (3,297 individuals) preregistration trial (an extensive CVOT in obese individuals without T2DM (SELECT) is expected to complete in 2024) HbA 1c was powerfully and durably reduced