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Because of the methyl trap, an intracellular functional folate deficiency can exist in the presence of normal, or even elevated, serum folate and B12 levels
Likewise, the origin of the glutathione that accumulates in this compartment remains unclear, as does whether external factors, such as glutathione-rich diets or direct intake of this compound as an antioxidant supplement, might influence its levels in the tumour microenvironment
In lab tests, scientists have discovered that glutathione reduces oxidative stress
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