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J Clin Immunol
Parnis FX, Coleman RE, Harper PG, et al
thus, this affinity for multiple receptors may allow IGF-1 to be tumorigenic in many types of cancer
Tannenbaum et al., 1983)
It is also based on the arginine paradox, discussed above, that despite an intracellular L-arginine concentration much higher than its K m for eNOS activity, high extracellular concentration of L-arginine can still promote NO production
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