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Clinical trials showed minimal adverse effects, and anecdotal reports from thousands of users confirm this
18 Malabsorption due to microbiome imbalance, gut barrier damage, chronic use of medications such as metformin and proton-pump inhibitors, and poor diet also increases the likelihood of low B12 levels
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Last reviewed: May 31, 2026 Last updated: May 31, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
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