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Here is a revised and more accurate explanation of the reasons a UK GP surgery might refuse to give a B12 injection a day earlier than scheduled, incorporating the points youve raised and providing a more scientifically grounded perspective: 1

Sensory issues: Brain injuries typically include sensory problems like blurred vision, sensitivity to light or sound, ringing in the ears or an inability to smell normally

Cognitive psychotherapy treatment decreases peripheral oxidative stress parameters associated with major depression disorder

Missing doses or doubling up disrupts the steady-state concentrations these peptides need for optimal appetite suppression and metabolic effects

Oxidative Medicine and Cellular Longevity , 2012, 324832