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Tomar 1 mL del extracto en un tubo de ensayo de 15 mL, aadir 9 mL de acetonitrilo, mezclar en vrtex durante 1 min, luego tomar una porcin en un tubo de centrfuga de 5 mL, centrifugar a 16000 r/min durante 5 min
10.1186/1472-6793-11-12 46 PangY.YuanX.GuoJ.WangX.YangM.ZhuJ.et al (2018)
2 Some patients present with what is termed papillary tip melanosis, and this is simply small brown, red, or dark pink focal pigmented specks on the tip or lateral border of the tongue
It is a requirement backed by clinical trial data showing that slower titration reduces gastrointestinal side effects by 40 to 60% compared to starting at full dose
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