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It also did not account for treatment duration, genetic risk factors, cancer stage, or tumor subtype
They are significantly higher in price than older, conventional diabetes treatments such as biguanides like metformin as Mounjaro and Ozempic are still on patent and are biologics, which tend to be more expensive given their complexity
The most common side effects include: Gastrointestinal issues: Nausea, vomiting, diarrhea, and constipation are typical when starting GLP-1 therapy
(2018) [online] Available at: [Accessed 25 Apr
Mechanism of Action GLP-1: Suppresses appetite, slows gastric emptying GIP: Enhances insulin secretion post-meal Glucagon: Increases energy expenditure and fat oxidation Preliminary trials showed up to 24.2% body weight loss over 48 weeks in obese participants exceeding results seen with Semaglutide or Tirzepatide in comparable timelines
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