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This finding is not unique to mice, as a similar response has been reported in musk shrews treated with direct injections of exenatide with and without exendin-9 into the AP and NTS (86)
It activates the same GLP-1 pathway semaglutide uses, but it also targets glucose-dependent insulinotropic polypeptide (GIP) receptors
Organ failure can occur, depending on the extent and severity of muscle damage, and is the cause of death in about 8% of cases (14)
Cheng serves as a consultant/advisory board member for Abbott Diabetes Care, AstraZeneca, Bayer, Boehringer Ingelheim, Dexcom, Eli Lilly and Company, HLS Therapeutics, Insulet, Janssen, Novo Nordisk, and Sanofi
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