The peptide raises production of growth factors, including vascular endothelial growth factor (VEGF), which drives new blood vessel formation, and epidermal growth factor (EGF), which supports cell growth and differentiation
Reconstituted peptides are already in solution, which creates more opportunity for degradation, contamination, pH-related instability, or oxidation over time
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(Frontiers in Pharmacology, 2022) reports a half-life under 30 minutes after IM or IV administration in rodent and dog models, which is why split-dose schedules appear in the literature