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Gpx4 cKO allele (generated by QR group) was crossed to Avil-Cre-ER to generate sensory neuron-specific Gpx4 KO mice
Interest peaked in this combination after early-phase studies revealed that activating both the GLP-1 system and amylin receptor pathways produced effects that appeared greater than simply adding the individual responsessuggesting true complementary action at the neurological level
Manag Care 22:7172 Niessl C, Boulesteix AL, Oh J, Palm K, Schlingmann P, Wygoda S, Haffner D, Wuhl E, Tonshoff B, Buescher A, Billing H, Hoppe B, Zirngibl M, Kettwig M, Moeller K, Acham-Roschitz B, Arbeiter K, Bald M, Benz M, Galiano M, John-Kroegel U, Klaus G, Marx-Berger D, Moser K, Mueller D, Patzer L, Pohl M, Seitz B, Treikauskas U, von Vigier RO, Gahl WA, Hohenfellner K (2022) Relationship between age at initiation of cysteamine treatment, adherence with therapy, and glomerular kidney function in infantile nephropathic cystinosis
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