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In addition to classical receptor signaling, selected microbiota-derived BAs metabolites can also influence immune-associated transcriptional regulators, thereby expanding the scope of BAs signaling in mucosal immune homeostasis
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The safety of incretin-based therapies The widespread extrapancreatic expression of GLP-1 and GIPR raises questions surrounding the long-term consequences of incretin-based therapies for type 2 diabetes and obesity
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