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Each escalation step roughly doubles the previous dose until reaching the 1.8 mg level, after which increases become more modest
After inducing ischemic AKI in 810-week-old, male C57BL/6 mice, mass spectrometry metabolomics revealed that the liver had the most distinct phenotype 24 h after AKI versus 4 h and 7 days
It appears as a white lyophilized powder
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doi:10.1182/blood.V53.5.851.851
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