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Climacteric 15:317319 Villareal DT, Shah K, Banks MR, Sinacore DR, Klein S (2008) Effect of weight loss and exercise therapy on bone metabolism and mass in obese older adults: a one-year randomized controlled trial

PI3K/Akt/mTOR activation Hits the central anabolic signalling cascade - the same pathway behind insulin's metabolic effects and most growth-factor-driven hypertrophy

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When serotonin levels are balanced, Oladunjoye added, then food cravings tend to decrease and people feel more satisfied with less food