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\n\n\n\n Large-scale human clinical trials are currently lacking
Caffeine Some studies have shown that moderate caffeine consumption reduces oxidative stress in the body
The bulk of evidence is pre-clinical, concentrated in skin, wound-healing, and hair-follicle research
PMID 8049254
The signal mediated by S1PR3 has also been shown to contribute to the high S1PR1 chemotactic property of MZ B cells, thereby affecting the trafficking of MZ B cells
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