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Nausea Vomiting Diarrhea Constipation Abdominal pain Indigestion Fatigue Though less common, serious side effects may include pancreatitis, gallbladder problems, kidney issues due to dehydration, and severe allergic or stomach reactions

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Other complications of chronic constipation include: Anal fissures are small tears in the delicate lining of the anus (Mayo Clinic 2012)

An important systemic consequence of AKI is its effects on energy metabolism and redox balance

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